Almost always one of three things is overriding your choice. Work through them in this order.

1. The theme is not set to Custom. Per button, per rotary and per LED colours can only be edited on the Custom theme. On any of the named themes (DNR, Racing, Arctic, Tokyo, Gulf Oil and the rest) the theme supplies the colours and your individual picks are locked. The plugin shows a message on the colour box when this is the reason.

2. Universal Theme is switched on. Universal Theme deliberately overrides every device so they all light in step, and it outranks the per device setting even when Custom is already selected. You will see "This wheel is using Universal Theme colours" on the locked control. Either edit the colour in Daniel Newman Racing > Settings > Theme, or turn Universal Theme off to customise that device on its own.

3. You edited a different preset from the one that loads. Presets are stored per device and per game. If you have a preset for the game you are in, that is the one that loads, so a change made on the Any game preset never appears. Check the CURRENT PRESET label at the top of the page while the game is running, and edit that one.

If the colour is correct everywhere in the plugin and still wrong on the device, check that the correct LED profile for that device is the one running in SimHub.